RecruitingNot Applicable

Acute Effects of Neurodynamics on Strength and Endurance in Athletes

United States45 participantsStarted 2026-06-15

Plain-language summary

This study explores the acute effects of neurodynamics, an intervention commonly used by physical therapist to improve nerve mobility and decrease pain, on the strength and muscular endurance in the athletic population. This study aims to find if these interventions can maintain or promote strength and endurance in the hamstrings. The studies results will help physical therapist better prescribe exercise and hands-on treatment for hamstring and sciatic nerve related conditions and injuries.

Who can participate

Age range

18 Years – 30 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Participants must be between 18 and 30 years of age. * Must be able to read, understand, and provide informed consent, in English. * Must be currently participating in an organized sport (e.g. collegiate, club, or competitive recreational level) or engaging in structured resistance training and athletic conditioning for recreational sports events (e.g 5k, marathon, Crossfit, Hyrox, etc). * Medically stable with no known contraindications to physical exertion. * Cleared for participation in strength or maximal-effort isometric testing. * Be able to perform lower extremity isometric testing without pain that limits maximal effort. * Must have 2 lower extremities capable to producing full range knee flexion and extension range of motion. * No medical condition that significantly alters lower extremity neuromuscular performance. * No history of lower extremity surgery in the past 12 months. Exclusion Criteria: * Individuals younger than 18 or older than 30. * Acute lower extremity injury in the last 12 weeks. * Lower extremity surgery within the last 12 months. * Pain in either lower extremity that would limit maximal physical exertion. * History of neurological disorders, including but not limited to: Neuropathy, Stoke, MS, Parkinson's Disease, etc. * Use of medications that significantly impact neuromuscular performance, strength or fatigue. * No supplementation that affects neuromuscular performance, strength, or fatigue. * Unable to read and understan…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Isometric Strength

Timeframe: From initial strength and endurance test, to the post intervention strength and endurance test, assessed during a single study visit, assessed up to 30 minutes.

Trial details

NCT IDNCT07721220

SponsorHigh Point University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-07

Contact for this trial

Dr. Tommy Wyat, DPT

856-381-6652 twyatt2@highpoint.edu

View on ClinicalTrials.gov More Sciatic Leg Pain trials