Cilostazol and Aspirin for Cardiovascular Event Prevention in Patients With Type 2 Diabetes (NCT07719894) | Clinical Trial Compass
RecruitingPhase 4
Cilostazol and Aspirin for Cardiovascular Event Prevention in Patients With Type 2 Diabetes
South Korea1,200 participantsStarted 2026-05-06
Plain-language summary
Patients with type 2 diabetes and cardiovascular risk factors are at increased risk of cardiovascular events. Therefore, a multi-center prospective randomized study will be conducted to compare the efficacy and safety of cilostazol and aspirin for the prevention of major adverse cardiac and cerebrovascular events (MACCE) in high-risk patients with type 2 diabetes.
Who can participate
Age range
19 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Individuals with type 2 diabetes mellitus were eligible if they were aged ≥19 years
* Individuals with subclinical atherosclerosis or metabolic syndrome, defined as at least one of the following:
* Carotid intima-media thickness ≥ 1 mm
* Ankle-brachial index \< 0.9 - Pulse wave velocity ≥ 9 m/s
* Flow-mediated vasodilatation \< 5%
* Coronary artery calcium score ≥ 40
* Coronary artery stenosis ≥ 20% or ≤ 70%
* Peripheral artery occlusive disease ≥ 20%
* Metabolic syndrome
* Individuals with HbA1c ≤ 9.9%
* Individuals who voluntarily agree to participate in the study and provide written informed consent
Exclusion Criteria:
* Patients with a history of major cardiovascular events, including myocardial infarction, stroke, or heart failure
* Patients with heart failure (NYHA I\~IV)
* Patients with current active bleeding or suspected bleeding
* Patients with suspected bleeding tendency or hematologic disorder, such as hemophilia or thrombocytopenia
* Patients recently diagnosed with gastrointestinal ulcerative disease
* Patients with inadequately controlled hypertension, defined as systolic blood pressure ≥ 180 mmHg or diastolic blood pressure ≥ 110 mmHg
* Patients with severe renal dysfunction, defined as estimated glomerular filtration rate \< 30 mL/min/1.73 m²
* Patients with liver enzyme levels greater than 3 times the upper limit of normal or chronic liver disease
* Individuals currently taking antiplatelet or antithrombotic agents
* Individuals who …
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Incidence of Major Adverse Cardiac and Cerebrovascular Events (MACCE)