Morning Activation to Improve Mood After Stroke (NCT07719517) | Clinical Trial Compass
RecruitingNot Applicable
Morning Activation to Improve Mood After Stroke
Hong Kong30 participantsStarted 2026-05-15
Plain-language summary
This pilot randomized controlled trial will evaluate the feasibility and preliminary effects of a six-week behavioral intervention designed to improve mood and daily functioning in adults who have experienced a stroke and report depressive symptoms and difficulty becoming engaged in activities after waking.
Participants will be randomly assigned to either the behavioral intervention or a health education program. Assessments will be completed before and immediately after the six-week program and will include questionnaires and seven-day monitoring of sleep, activity, and mood. The study will also examine feasibility indices such as participant retention, intervention attendance, acceptability, and preliminary changes in mood.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 18 years or older.
* History of stroke at least 6 months before enrollment.
* Patient Health Questionnaire-9 score of 10 or higher.
* Difficulty getting started or engaging in activities in the morning.
* Able to provide informed consent.
Exclusion Criteria:
* Conditions that would interfere with study participation.
* Neurological condition other than stroke.
* Currently receiving psychological therapy for depression.
* Significant cognitive impairment or dementia.
* Current or past diagnosis of psychosis, bipolar disorder, or mania.
* Hospitalization that would interfere with study participation.
* Acute or significant suicidal ideation
* Alcohol or substance use problems within the past month.
* Use of antidepressant or anti-anxiety medication unless the dosage has been stable for at least 4 weeks and no changes are planned during the study.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Recruitment Rate
Timeframe: From the start of recruitment until enrollment of the final participant.
2
Retention Rate
Timeframe: Immediately after completion of the 6-week intervention
3
Intervention Attendance
Timeframe: Throughout the 6-week intervention period
4
Intervention Acceptability
Timeframe: Immediately after completion of the 6-week intervention
5
Participants Experiencing Adverse Events
Timeframe: From enrollment through completion of the immediate post-intervention assessment.