RecruitingNot Applicable

Sleep More, Stress Less: 90-Day Trial of Neuralli Mood

United States100 participantsStarted 2026-06-30

Plain-language summary

This decentralized, single-arm study evaluates the effects of 90 days of daily Neuralli Mood supplementation on perceived stress, sleep disturbance, mood, anxiety, depressive symptoms, happiness, and occupational burnout in adults experiencing stress or occasional sleep disruption. Participants serve as their own controls, completing validated self-report measures before beginning supplementation and again after the 90-day intervention, with safety and adherence check-ins during the study.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 18 years or older and able to provide informed consent. * Generally healthy adult experiencing stress, occasional sleep disruption, low mood, anxiety symptoms, or work-related burnout. * Willing and able to take two capsules of Neuralli Mood daily for 90 days. * Willing and able to complete electronic baseline, follow-up, adherence, and safety assessments. * Has reliable access to the internet and an email-enabled device. Exclusion Criteria: * Pregnant or nursing. * Known allergy or hypersensitivity to Neuralli Mood, probiotics, or any product ingredient. * Severe or unstable gastrointestinal disease, including a condition for which probiotic use may be inappropriate. * Immunocompromised status or current immunosuppressive therapy. * Severe or unstable mood disorder, acute psychiatric symptoms, or a current risk of harm to self or others. * A clinically significant sleep disorder for which participation or changes in symptoms should be managed by a healthcare professional. * Cognitive impairment or another condition that prevents informed consent or reliable completion of study procedures. * History of a severe allergic reaction when the investigator determines probiotic use may present an unacceptable risk. * Use of a medication or presence of a medical condition for which a healthcare professional advises against probiotic supplementation. * Any other circumstance that, in the investigator's judgment, makes participation inappropriate or unsafe.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in Depression Anxiety and Stress Scales-21 Stress Subscale Score

Timeframe: Baseline before the first dose and end of the 90-day supplementation period

Change in PROMIS Sleep Disturbance Score

Timeframe: Baseline before the first dose and end of the 90-day supplementation period

Trial details

NCT IDNCT07717385

SponsorEfforia, Inc

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2027-09-28

Contact for this trial

Matthew Amsden

+13232844626 help@efforia.com

View on ClinicalTrials.gov More Psychological Stress trials