ADHD, Gut Problems and Synbiotic (NCT07717359) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
ADHD, Gut Problems and Synbiotic
174 participantsStarted 2026-09
Plain-language summary
The scope of this study is to evaluate the impact of a synbiotic product (a combination of probiotic bacteria and prebiotics) on symptoms reported by participants with ADHD. The main focus is to study the efficacy of the synbiotic product as compared to a placebo in improving emotion regulation and gut-health associated symptoms in adults with ADHD.
Who can participate
Age range
18 Years – 64 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* ADHD-diagnosis
* Self-described gastrointestinal problems
* Has not previously consumed Synbiotics
* Be prepared to avoid supplements with lactic acid bacteria, calcium and vitamin B6, B9, and B12, starting from washout
Exclusion Criteria:
* Has consumed antibiotics within the previous 6 weeks
* Has a serious disease that requires treatment and/or leads to a weakened immune system
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is listed as 'not yet recruiting' — do you know when it's expected to open, and would it make sense for us to wait for it or pursue other options in the meantime?
2The study is focusing on a synbiotic (a combination of probiotics and prebiotics) for children with ADHD who also have gut problems — given my child's specific GI symptoms alongside their ADHD, do you think this kind of gut-focused approach is worth exploring?
3The main thing being measured is emotion regulation after 12 weeks using a scale called the DERS-16 — how reliable is that kind of scale for tracking real-world changes in emotional control, and would 12 weeks be long enough to know if it's actually helping?
4Since this trial is listed as Phase NA, meaning it may be a pilot or feasibility study, what does that mean for how much we'd actually know about safety and effectiveness before my child participates?
5If my child were to join this trial, are there standard ADHD treatments we'd have to pause or avoid during the 12 weeks, and is that a trade-off you'd feel comfortable with given where we are in their treatment right now?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change from baseline in the total score of Difficulties Regulation Scale 16 (DERS-16) after 12 weeks of intervention.