From Prehabilitation to Rehabilitation (Prehab2Rehab): Digitally Supported Short-Term Prehabilita… (NCT07716761) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
From Prehabilitation to Rehabilitation (Prehab2Rehab): Digitally Supported Short-Term Prehabilitation Prior to Cardiac Surgery
Austria40 participantsStarted 2026-08-01
Plain-language summary
Prehab2Rehab is a prospective single-arm feasibility study evaluating the implementation of a multimodal, digitally supported prehabilitation program for adults awaiting elective cardiac surgery. During the routine preoperative waiting period, participants receive individualized education, psychosocial support, nutritional counselling, home-based physical activity guidance, and digital self-management support. The study aims to determine the feasibility, acceptability, usability, and safety of integrating this multidisciplinary prehabilitation pathway into routine clinical care. Exploratory outcomes include functional capacity, psychological well-being, nutritional status, digital engagement, and selected perioperative clinical outcomes to inform the design of future confirmatory trials.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
\- Age ≥ 18 years
* Classification as New York Heart Association (NYHA) functional class I-II
* Low surgical risk profile, defined as a EuroSCORE between 0 and 3
* Scheduled for one of the following elective cardiac surgical procedures:
* Open-heart valve surgery
* Coronary artery bypass grafting (CABG)
* Combined valve surgery and CABG
* Surgical closure of an atrial septal defect (ASD)
* Primary residence in Vienna to ensure the feasibility of in-person assessments and supervised sessions
* Sufficient German language proficiency to participate in assessments and educational components
* Adequate digital literacy to engage with the digital support tools used in the intervention
* Clinical and physical assessment confirming that participation in exercise training is medically safe
Exclusion Criteria:
* Emergency, urgent, or otherwise non-elective cardiac surgery
* Highly complex or specialized surgical procedures (e.g., aortic aneurysm repair, cardiac tumor resections)
* Interventional cardiac procedures (e.g., transcatheter aortic valve implantation \[TAVI\], MitraClip interventions)
* Neuromotor or physical impairments that might prevent adherence to the study protocol or informed participation
* Contraindications to spiroergometry according to current guidelines:
Absolute contraindications:
* Acute coronary syndrome
* Symptomatic cardiac arrhythmias and/or hemodynamic instability
* Decompensated heart failure
* Acute pulmonary embolism
* …
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Proportion of eligible patients providing written informed consent (Recruitment rate)
Timeframe: From study initiation until completion of recruitment (approximately 6 months)
2
Proportion of enrolled participants completing the study (Participant retention)
Timeframe: From baseline until completion of follow-up after Phase II cardiac rehabilitation (approximately 4-6 months)
3
Proportion of completed intervention components (Adherence to the prehabilitation program)
Timeframe: Throughout the preoperative intervention period (approximately 6-10 weeks)
4
Proportion of completed study assessments and available study data (Data completeness)
Timeframe: From baseline until completion of follow-up after Phase II cardiac rehabilitation (approximately 4-6 months)
5
Participant-reported usability and acceptability scores for the digital support tools
Timeframe: At the preoperative assessment following completion of the prehabilitation program (approximately 6-10 weeks after baseline)
6
Number, severity, and type of intervention-related adverse events
Timeframe: From enrolment until completion of the prehabilitation program (approximately 6-10 weeks)
Trial details
NCT IDNCT07716761
SponsorLudwig Boltzmann Institute for Digital Health and Prevention