For an Investigator-led Hair Study Comparing Between Healthy and Hair Loss Volunteers (NCT07716748) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
For an Investigator-led Hair Study Comparing Between Healthy and Hair Loss Volunteers
66 participantsStarted 2026-08
Plain-language summary
This study is to evaluate differences in the gut and follicle/scalp microbiome signature in AGA compared to a non-AGA population. Also, to investigate differences in inflammation and other biomarkers in AGA compared to non-AGA population at baseline and after a successful treatment
Who can participate
Age range
21 Years – 45 Years
Sex
MALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Male volunteer from 21 to 45 years old
. Volunteer with BMI between 18.5 to 30 kg/m2
. Volunteer willing and able to fulfill the study requirements and schedule
. Volunteer willing to give their stool sample, as well as swabs, follicles, and blood.
. Volunteer informed about the study objectives and procedures, and able to understand them
. Volunteer who has given written informed consent
. Volunteer in overall good health
. Volunteer with no diagnosis of hair loss or other condition or treatment susceptible to impact hair count and microbiome.
Exclusion criteria
. Volunteer with severe gastro-intestinal symptoms (including gluten and lactose intolerance)
. Volunteer with auto-immune disease, diabetes; hyper or hypo-thyroidism ; chronic kidney failure
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Norwoord-Hamiton scale hairloss severity
Timeframe: 6 months
2
Change in hair density
Timeframe: 6 months
3
Metabolomic profiling of the stool
Timeframe: 6 months
4
Gut and Scalp/Follicle Microbiome Signature Differences at Baseline
Timeframe: Baseline
5
Change in proteomic profile
Timeframe: 6 months
6
Change in Gene Expression Profiles (Transcriptomics)
. Volunteer with diagnosis of scalp-related disease such as folliculitis, lichen planopilaris, folliculitis decalvans, tinea capitis, head lice, or seborrheic dermatitis
. Volunteer undergoing hypertension treatment
. Volunteer who undertook any oral anti-hair loss pharmaceutical treatment in the past 3 months (e.g. Finasteride)
. Volunteer who undertakes any hormone-disrupting drug
. Volunteer who used topical minoxidil or other pharmaceutical-grade topical hair restorers in the past 3 months
. Volunteer with a total dandruff score above 1 on the L'Oreal Dandruff scale.