Comparison Between Eccentric Hamstring Training and Sprint-Specific Training (NCT07716319) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Comparison Between Eccentric Hamstring Training and Sprint-Specific Training
United States90 participantsStarted 2026-09
Plain-language summary
The purpose of this study is to compare the effects of an intensity-, volume-, and time under tension-matched eccentric hamstring exercise intervention with the Romanian deadlift (RDL) and the Nordic hamstring exercise (NHE) to a sprint-specific training program on hamstring muscle architecture, volume, sprint performance, strength, and power.
Participants will be assigned to complete one of the 3 hamstring interventions for 10 weeks.
Who can participate
Age range
18 Years – 25 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 18-25 years
* Actively participating in a club team
* \>6 months experience with resistance training
* Minimum of 1 year experience at the high school level in organized team sport
* No history of hamstring injury within the last 6 months
* No history of major lower extremity surgery (including back)
* No acute musculoskeletal injury to the lower extremity
* Not currently pregnant
Exclusion Criteria:
* Unable to refrain from resistance training outside the study
* Unable to make at least 80% of the training sessions
* Hamstring injury in the last 6 months
* History of major lower extremity surgery (including back)
* Acute musculoskeletal injury to the lower extremity
* Currently pregnant
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in fascicle length (FL)
Timeframe: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)
2
Change in muscle cross-sectional area (CSA)
Timeframe: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)
3
Change in muscle volume
Timeframe: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)
4
Change in pennation angle (PA)
Timeframe: Baseline to Mid-intervention (6 weeks), Post-intervention (10 weeks), and Post 2 week de-training (12 weeks)