Effect of Different Bioactive Restorative Materials and Techniques on Pulpal Condition (NCT07715383) | Clinical Trial Compass
CompletedNot Applicable
Effect of Different Bioactive Restorative Materials and Techniques on Pulpal Condition
Egypt30 participantsStarted 2026-03-15
Plain-language summary
Restorative materials play a crucial role in dental treatments, particularly in managing tooth decay and restoring damaged teeth. Their interaction with dental pulp is significant, especially in cases where pulp inflammation is present.
When a tooth is compromised, the choice of restorative material can influence the health of the pulp. Certain materials can promote healing and reduce inflammation, while others may exacerbate the condition. For instance, biocompatible materials like glass ionomer or resin-modified glass ionomer have been shown to provide a favorable environment for pulp cells, potentially aiding in the regeneration of dental pulp tissue.
Conversely, materials that are not well-tolerated may lead to further irritation and inflammation, highlighting the importance of selecting appropriate restorative materials to protect pulp vitality and support overall dental health.
Who can participate
Age range
21 Years – 50 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Simple occlusal deep carious lesions.
* ICDAS 5 and 6.
* No restorations with the related teeth.
* Periodontally healthy patient (no bleeding on probing and no radiographic evidence of periodontal bone loss)
* Normal occlusion.
* Participants willing to commit for the entire period of the trial and agreed to sign the written consent after full explanation of the study.
Exclusion Criteria:
* Vulnerable groups such as pregnant females, breast feeding, prisoners, mentally ill, etc.…
* Cigarette smoking or any form of tobacco consumption.
* Medically compromised patients as diabetes.
* A previously endo treated teeth.
* Ongoing dental or periodontal treatment 12 months before the beginning of the study.
* Presence of periodontal pockets \>3 mm in the affected tooth.
* Antibiotics or any medication that might lead to decreased salivary flow.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.