Midlife Empowerment and Longevity Through Optimizing Wellness (NCT07713862) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Midlife Empowerment and Longevity Through Optimizing Wellness
200 participantsStarted 2027-01
Plain-language summary
The goal of this observational longitudinal study is to understand how lifestyle behaviours, menopausal symptoms, and digital health data change over time in women experiencing perimenopause or menopause, and to evaluate whether a personalised digital health programme can support healthier lifestyle behaviours and improve cardiometabolic health.
The main questions it aims to answer are:
1. Can personalised lifestyle recommendations informed by wearable devices, dietary logging, and self-reported symptoms improve adherence to healthy diet, physical activity, and sleep behaviours?
2. How are menopausal symptoms associated with changes in cardiometabolic health, body composition, physical function, and quality of life over time?
Participants will:
1. Attend study visits at the National University of Singapore for health assessments, including measurements of body composition, physical function, and cardiometabolic health.
2. Wear a smartwatch or wearable device to monitor physiological and activity data throughout the study.
3. Use a mobile application to record dietary intake, menopausal symptoms, and other health-related information.
4. Receive personalised lifestyle recommendations based on their health data and engage in regular follow-up assessments over the study period.
Who can participate
Age range
21 Years – 65 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Women aged 21-65 years old;
* Report at least mild climacteric symptoms as indicated by an MRS score ≥5;
* Waist circumference ≥80 cm, indicating abdominal adiposity;
* Own and use a smartphone compatible with the CGM and Oura Ring.
Exclusion Criteria:
* Are currently receiving hormone replacement therapy (HRT);
* Are currently using oral contraceptives;
* Have been diagnosed with severe psychiatric illness requiring inpatient care;
* Are concurrently enrolled in another behavioural or psychotherapy trial;
* Have significant cognitive impairment or inability to engage with digital tools;
* Have uncontrolled chronic medical conditions that may interfere with study participation;
* Unable to comprehend written and spoken English.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Menopause Rating Scale (MRS)
Timeframe: Change in Menopause Rating Scale (MRS) score from enrolment to 6 month mark
Trial details
NCT IDNCT07713862
SponsorNational University Health System, Singapore