Biomarkers for Endometriosis (NCT07713797) | Clinical Trial Compass
RecruitingNot Applicable
Biomarkers for Endometriosis
Canada100 participantsStarted 2026-01-16
Plain-language summary
Endometriosis is a condition in which tissue similar to the lining of the uterus grows outside the uterus, often causing pain and infertility. Currently, endometriosis can only be definitively diagnosed through invasive procedures like laparoscopy and biopsy.
The purpose of this study is to investigate whether the proteins Synuclein Gamma (SNCG) and B-Cell Lymphoma 6 (BCL6), measurable in blood and menstrual fluid, can serve as non-invasive biomarkers to diagnose or monitor endometriosis.
Who can participate
Age range
18 Years – 45 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria for Endometriosis Group:
* Women of reproductive age group (18Y-45Y).
* Women with active endometriosis diagnosed by ultrasound/MRI/laparoscopy.
Exclusion Criteria for Endometriosis Group:
* Women \<18Y and \>45Y.
* Women with endometriosis during stimulation with gonadotropins.
* Current or prior history of uterine, ovarian, colon, pancreatic, breast or any other type of cancer.
* Any prior history of chronic illness.
* Pregnant women.
Inclusion Criteria for Control Group:
* Women of reproductive age group (18Y-45Y).
* Women without endometriosis and any other gynaecological problem.
Exclusion Criteria for Endometriosis Group:
* Women \<18Y and \>45Y
* Prior history of any disease including cancer or chronic illness.
* Pregnant women.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Synuclein Gamma (SNCG) and B-cell Lymphoma 6 (BCL-6) Levels
Timeframe: Baseline for control participants and baseline and approximately 3 months after treatment for participants with endometriosis