Active — Not RecruitingNot Applicable

TCP-600 Supplementation and Performance Response in Professional Football Players

Poland65 participantsStarted 2026-08-06

Plain-language summary

This study will examine whether a 28-day supplementation protocol containing taurine, caffeine, and phosphatidylserine can help professional male football players maintain physical performance, cognitive function, recovery-related readiness, and selected football-specific perceptual-cognitive performance. Participants will be randomly assigned to receive either placebo or a phosphatidylserine-containing multi-ingredient supplement. Before and after the supplementation period, players will complete non-invasive assessments such as sprint testing, reaction-time testing, heart rate variability monitoring, wellness/readiness questionnaires, mental-fatigue measures, and selected football-specific perceptual-cognitive tasks where available. The study is designed as an external validation and extension of responder profiles derived from previous randomized controlled trials. Data from previous trials and this validation cohort will be used to examine whether baseline physical, cognitive, autonomic, fatigue-related, recovery-related, or perceptual-cognitive characteristics can predict which players are most likely to benefit from phosphatidylserine-containing multi-ingredient supplementation.

Who can participate

Age range

18 Years – 37 Years

Sex

MALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Male professional or highly trained football players aged 18-37 years. * Regular participation in structured football training and team activities. * Minimum of 5 years of structured football training experience. * Regular involvement in club training during the study period. * Medical clearance or no known contraindications to high-intensity exercise testing. * Ability to complete sprint, reaction-time, cognitive-fatigue, heart-rate-variability, wellness/readiness, and selected football-specific perceptual-cognitive assessments where available. * Willingness to maintain usual diet and training habits during the study period. * Willingness to avoid additional ergogenic supplements outside the study protocol during the intervention. * Willingness to follow caffeine restrictions before testing sessions. * Written informed consent provided before participation. Exclusion Criteria: * Current musculoskeletal injury or illness preventing full participation in training or testing. * Musculoskeletal injury within the previous 3 months that may affect sprint, football-specific performance, or perceptual-cognitive testing. * Cardiovascular, metabolic, neurological, psychiatric, or other chronic disease that may affect safety or study outcomes. * Diagnosed sleep disorder. * Use of medication affecting heart rate, autonomic nervous system function, sleep, cognition, or exercise performance. * Known hypersensitivity or intolerance to caffeine, taurine, phosphatidy…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Proportion of Participants Classified as Multidimensional Responders After 28 Days

Timeframe: Baseline to post-intervention after 28 days of supplementation

Trial details

NCT IDNCT07710547

SponsorVizja University in Warsaw

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-08-10

View on ClinicalTrials.gov More Athletic Performance trials