Safety and Effectiveness of Mosaic for the Treatment of Midface Volume Deficit

Inclusion Criteria: Subjects: * Who at baseline, demonstrate bilateral and symmetrical volume deficit in their midface of grades moderate or severe on the CMVDS based upon live image scoring (i.e., both the left and right sides of the face must be graded independently, and both sides must score grades of either moderate or severe to be eligible).. * Who, if male, agree to be clean-shaven at each study visit. Exclusion Criteria: Subjects: * Who are an employee or relative of an employee of the clinical site or study sponsor (e.g., immediate family, household members). * Who may have any physical attributes such as skin lesions, tattoos, or other issues in the midface that may, in the investigator's judgment, interfere with effectiveness assessments or study treatments. * With active skin disease within the past 6 months or with a history of precancerous lesion or skin malignancies in the midface that may, in the investigator's judgment, interfere with effectiveness assessments or study treatments. * With a known allergy to any of the components of Mosaic, including hyaluronic acid, lidocaine, and bovine collagen. * With a history of hypertrophic scarring and/or keloid scarring. * With active autoimmune disease. * With a history of anaphylactic shock. * Who are taking any anticoagulation therapy or medications which may increase bleeding including warfarin and DOACS within 7 days of any treatment. * Who have a history of a coagulation disorder. * Who are using prescription…