LD/CD (medications to treat Parkinson's disease) will be delivered using an assembly of nested sachets made of permeable material. The assembly is placed in the oral/buccal cavity (between cheek and gum of lower jaw) and delivers continuous release of CD and LD for both transmucosal and gastrointestinal absorption. The combination of CD/LD in the inner sachet varies from that in the outer sachet. This allows for sequential release of CD and then LD to mimic a CD pretreatment method which is known to increase LD absorption and prolong its half-life.
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Blood CD Level - Minute 15
Timeframe: Minute 15 after administration
Blood LD Level - Minute 15
Timeframe: Minute 15 after administration
Blood CD Level - Minute 30
Timeframe: Minute 30 after administration
Blood LD Level - Minute 30
Timeframe: Minute 30 after administration
Blood CD Level - Minute 45
Timeframe: Minute 45 after administration
Blood LD Level - Minute 45
Timeframe: Minute 45 after administration
Blood CD Level - Hour 1
Timeframe: One hour after administration
Blood LD Level - Hour 1
Timeframe: One hour after administration
Blood CD Level - Hour 2
Timeframe: Two hours after administration
Blood LD Level - Hour 2
Timeframe: Two hours after administration
Blood CD Level - Hour 3
Timeframe: Three hours after administration
Blood LD Level - Hour 3
Timeframe: Three hours after administration
Blood CD Level - Hour 4
Timeframe: Four hours after administration
Blood LD Level - Hour 4
Timeframe: Four hours after administration
Blood CD Level - Hour 5
Timeframe: Five hours after administration
Blood LD Level - Hour 5
Timeframe: Five hours after administration
Blood CD Level - Hour 6
Timeframe: Six hours after administration
Blood LD Level - Hour 6
Timeframe: Six hours after administration
Blood CD Level - Hour 7
Timeframe: Seven hours after administration
Blood LD Level - Hour 7
Timeframe: Seven hours after administration
Blood CD Level - Hour 8
Timeframe: Eight hours after administration
Blood LD Level - Hour 8
Timeframe: Eight hours after administration