The goal of this study is to scientifically evaluate the efficacy of this oil pulling oral rinse in reducing dental plaque, gingival inflammation, gingival bleeding, and selectively reducing caries- and periodontal disease-associated bacteria compared to a marketed mouthwash and a placebo oral rinse
Who can participate
Age range
18 Years – 70 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Adult subjects aged 18-70, that are in good health.
. Subject must have:
. Baseline gingival inflammation (MGI) score of at least 1.80.
. Baseline gingival bleeding (GBI) score of ≥ 1 on at least 20 sites.
. An overnight (12 to 18 hour abstention from any oral hygiene) dental plaque (mean) score greater than 0.6 according to the RMNPI Index.
. Have a minimum of 20 'scorable' teeth (excluding 3rd molars).
. The subjects should understand the information provided about the investigative nature of the treatment, possible benefits and side effects. Subjects will sign the Informed Consent Form.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Modified Gingival Index (MGI)
Timeframe: Baseline to 8 weeks
2
Gingival Bleeding Index (GBI)
Timeframe: Baseline to 8 weeks
3
Rustogi Modified Navy Plaque Index (RMNPI)
Timeframe: Baseline to 8 weeks
4
Measurement of plaque microbiome analysis
Timeframe: Baseline to 8 weeks
Trial details
NCT IDNCT07706647
SponsorThe University of Texas Health Science Center at San Antonio
. The subjects should be willing to comply with the study procedure and schedule, including the follow-up visits.
Exclusion criteria
. Current or history of oral cavity cancer or oropharyngeal cancer.
. Subject with destructive periodontal disease or those on antibiotic or anti-inflammatory drugs.
. Pacemaker or internal defibrillator, or any other active electrical implant anywhere in the body.
. Pregnant or nursing by subject report.
. Known allergic reaction to any of the study mouthwashes or any of their component.
. Any active condition, including but not limited to advanced periodontal disease or severe gingival recession, in the oral cavity at the discretion of the investigator.
. Any surgery or recent dental procedure in the oral cavity within 3 months prior to treatment, or before complete healing.