RecruitingNot Applicable

Comparison of Two Quantitative EMG Monitors for Deep Neuromuscular Block in Laparoscopic/Robotic and VATS Surgery

United States35 participantsStarted 2026-02-09

Plain-language summary

The main objective of the study is to compare the frequency of intraoperative spontaneous diaphragmatic movements and breath-initiation efforts in participants undergoing robotic and/or thoracic surgery under deep neuromuscular blockade (NMB), using either the TetraGraph or TwitchView applied to the dominant hand. These events will serve as objective indicators to evaluate each device's ability to monitor and maintain adequate deep NMB.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult male or female patients aged ≥ 18 years old. * Patients undergo elective abdominal laparoscopic/robotic or thoracic video-assisted (VAT) surgeries requiring general anesthesia for greater than 3 hours at The Ohio State University Wexner Medical Center. * Able to provide a signed, written informed consent. * Able to speak, read, and write in English. * ASA physical status I-III. Exclusion Criteria: * Patients who require emergency surgery or an emergent intervention. * Any documented cognitive or psychological disorders that, in the investigator's opinion, can interfere with the patient's pain perception. * Vulnerable populations: pregnant females, prisoners, breastfeeding. * Presence of any medical condition that, in the opinion of the principal investigator, should exclude the patient from the study (patients with pre-existing neuromuscular diseases. * Allergy or contraindications to any of the anesthetics, NMB agents, or sugammadex. * Patients with anatomical abnormalities of the hands or arms that prevent proper placement of the sensors for nerve stimulation. * Limited access to the monitoring area due to surgical positioning. * Patients with peripheral vascular disease, since it may affect measurement accuracy.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Incidence of intraoperative diaphragmatic movement during deep neuromuscular blockade

Timeframe: During maintenance of deep neuromuscular blockade throughout the surgical procedure, from achievement of deep neuromuscular blockade after induction of general anesthesia until completion of surgery prior to emergence.

Incidence of spontaneous breath-initiation efforts during deep neuromuscular blockade

Trial details

NCT IDNCT07706504

SponsorOhio State University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-02-09

Contact for this trial

Alberto Uribe, MD

6142933559 alberto.uribe@Osumc.edu

View on ClinicalTrials.gov More Neuromuscular Blockade trials