CompletedNot Applicable

Role Of Fixed Prosthodontic Restorations on Metabolic Control of Ischemic Heart Disease Patients

Egypt90 participantsStarted 2024-01-01

Plain-language summary

This study evaluated the effect of fixed prosthodontic rehabilitation on metabolic parameters and masticatory efficiency in patients with ischemic heart disease. Clinical and laboratory outcomes was assessed before and after treatment.

Who can participate

Age range

45 Years – 70 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

inclusion criteria * Patients aged 45 to 70 years with diagnosed stable ischemic heart disease. * Patients presenting with partial edentulism and compromised masticatory function due to missing teeth. * Patients indicated for fixed prosthodontic rehabilitation. * Patients with complete clinical records and laboratory data available at baseline and 6 months after treatment. * Patients who provided informed consent for treatment and use of their clinical data. Exclusion criteria * uncontrolled systemic diseases affecting metabolic status (e.g., uncontrolled diabetes mellitus). * acute cardiovascular events or unstable ischemic heart disease. * Patients with conditions affecting oral function other than tooth loss (e.g., neuromuscular disorders). * Patients who received removable prostheses instead of fixed prosthodontic rehabilitation. * Patients with incomplete clinical records or missing baseline or 6-month laboratory data.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in Hemoglobin A1c (HbA1c)

Timeframe: Baseline and 6 months after fixed prosthodontic rehabilitation

Change in High-Density Lipoprotein Cholesterol (HDL-C)

Timeframe: Baseline and 6 months after fixed prosthodontic rehabilitation

Change in Low-Density Lipoprotein Cholesterol (LDL-C)

Timeframe: Baseline and 6 months after fixed prosthodontic rehabilitation

Trial details

NCT IDNCT07705672

SponsorDr. Moaz Mohamed

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-09-12

View on ClinicalTrials.gov More Ischemic Heart Disease trials

Who can participate

Age range

45 Years – 70 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in Hemoglobin A1c (HbA1c)

Timeframe: Baseline and 6 months after fixed prosthodontic rehabilitation

Change in High-Density Lipoprotein Cholesterol (HDL-C)

Timeframe: Baseline and 6 months after fixed prosthodontic rehabilitation

Change in Low-Density Lipoprotein Cholesterol (LDL-C)

Timeframe: Baseline and 6 months after fixed prosthodontic rehabilitation