High-Intensity Peripheral Magnetic Stimulation in Traumatic Peripheral Nerve Injury (NCT07705490) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
High-Intensity Peripheral Magnetic Stimulation in Traumatic Peripheral Nerve Injury
Turkey (Türkiye)40 participantsStarted 2026-08
Plain-language summary
Traumatic peripheral nerve injury is a common cause of chronic neuropathic pain, muscle weakness, and functional limitation, particularly in young and active individuals. Current conservative and pharmacological treatments often provide incomplete relief or carry side effects. High-intensity peripheral magnetic stimulation (PMS) is a non-invasive method that may help reduce neuropathic pain and support motor recovery, but evidence in traumatic nerve injury is limited.
This randomized, double-blind, sham-controlled trial aims to evaluate whether high-intensity PMS, added to a standardized therapeutic exercise program, improves pain, function, quality of life, and electrophysiological measures in adults with traumatic peripheral nerve injury. Participants will be randomly assigned to receive either active PMS or sham PMS, in addition to the same exercise program. Outcomes will be assessed at baseline, 4 weeks, and 8 weeks.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age between 18 and 65 years
* Traumatic peripheral nerve injury
* Unilateral traumatic peripheral neuropathy confirmed by electromyography (EMG)
* Nerve injury occurring at least 3 months prior
* Douleur Neuropathique 4 (DN4) score ≥ 4
* Visual Analog Scale (VAS) score ≥ 4
* Manual Muscle Testing score \< 5
* No analgesic use, or stable analgesic therapy for the past month (no dose changes)
Exclusion Criteria:
* Active infection or malignancy
* Metal implant or shrapnel in the application area
* Electronic implants (e.g., cardiac pacemaker, spinal cord stimulator, deep brain stimulator)
* Central nervous system diseases
* Non-traumatic causes of neuropathy (e.g., radiculopathy, diabetic neuropathy, entrapment neuropathies, HIV-related neuropathy, trigeminal neuralgia)
* Complete nerve injury
* Injury involving three or more peripheral nerves or plexus injury
* History of peripheral nerve surgery or injection within the past 3 months
* Active psychiatric illness
* Coagulopathy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Pain Severity Measured by Visual Analog Scale (VAS)
Timeframe: Baseline, week 4, and week 8
Trial details
NCT IDNCT07705490
SponsorGaziler Physical Medicine and Rehabilitation Education and Research Hospital