Evaluation of Autogenous Bone Graft on Immediate Dental Implant Osseointegration Using Piezosurgery (NCT07705399) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Evaluation of Autogenous Bone Graft on Immediate Dental Implant Osseointegration Using Piezosurgery
Egypt20 participantsStarted 2025-05-17
Plain-language summary
This clinical study aims to evaluate the clinical and radiographic outcomes of immediate dental implant placement in mandibular premolar sites. Patients requiring extraction of mandibular premolars will receive immediate implant placement, with or without autogenous bone grafting, according to the study protocol.
When indicated, autogenous bone graft will be harvested using piezosurgery during the implant procedure. Participants will be followed up clinically and radiographically to assess implant stability, marginal bone level changes, and peri-implant tissue conditions over a defined follow-up period. The results of this study may help determine the effectiveness and predictability of immediate implant placement in mandibular premolar regions.
Who can participate
Age range
25 Years – 45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients requiring extraction of mandibular premolars.
* Age ≥ 25 years.
* Adequate oral hygiene and motivated patients for implant treatment.
* Sufficient bone volume to allow immediate implant placement (with or without minor augmentation).
* Patients willing to participate and attend follow-up visits for at least 6 months.
* Systemically healthy patients (ASA I or II).
Exclusion Criteria:
* Uncontrolled systemic diseases (e.g., uncontrolled diabetes, immunocompromised patients).
* Heavy smokers (e.g., \>10-15 cigarettes/day).
* Active periodontal or acute infection at the implant site.
* Poor oral hygiene or non-compliant patients.
* Pregnancy or lactation.
* History of radiotherapy in head and neck region.
* Severe bone deficiency not suitable for immediate implant placement.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.