QLESP Block for Pain Control in Robotic Partial Nephrectomy (NCT07704970) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
QLESP Block for Pain Control in Robotic Partial Nephrectomy
China120 participantsStarted 2026-07-20
Plain-language summary
The goal of this clinical trial is to learn if an ultrasound-guided nerve block called QLESP works to reduce pain and the need for strong pain medicines after robotic kidney surgery in adults. The main questions it aims to answer are:
1. Does QLESP reduce the total amount of opioid pain medicine participants need in the first 48 hours after surgery?
2. Does QLESP lower pain scores and improve recovery quality after surgery? Researchers will compare participants who receive QLESP block to participants who receive the same numbing medicine injected only at the surgical wound sites.
Participants will:
1. Be randomly assigned to receive either QLESP or local wound injection before surgery.
2. Have a patient-controlled pain pump for 48 hours after surgery.
3. Complete pain scores and recovery quality questionnaires at 2, 6, 12, 24, 48, and 72 hours after surgery.
4. Be followed until hospital discharge.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged 18 to 75 years
* Scheduled for elective robot-assisted partial nephrectomy (RAPN)
* American Society of Anesthesiologists (ASA) physical status I to III
* Body mass index (BMI) 18 to 35 kg/m²
* Voluntarily signed informed consent form Able to understand pain scoring and use of patient-controlled analgesia (PCA)
Exclusion Criteria:
* Language, communication, or comprehension barriers
* Infection at the intended puncture site
* Coagulopathy or bleeding diathesis
* Known allergy or contraindication to local anesthetics or opioids
* Use of analgesic medications within the past 3 months
* Peripheral neuropathy
* Severe cardiac, hepatic, or renal dysfunction
* Pregnancy or breastfeeding
* Refusal to participate in the study
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Cumulative Opioid Consumption at 48 Hours Postoperatively
Timeframe: From the end of surgery to 48 hours postoperatively.
Trial details
NCT IDNCT07704970
SponsorHuazhong University of Science and Technology