Preoperative 3D Magnetic Resonance Elastography for Predicting Surgical Risk in Patients Undergoi… (NCT07704203) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Preoperative 3D Magnetic Resonance Elastography for Predicting Surgical Risk in Patients Undergoing Hepatectomy
150 participantsStarted 2026-08-01
Plain-language summary
How to accurately and safely evaluate regional liver function before hepatectomy remains an important unsolved problem in the surgical management of hepatocellular carcinoma (HCC). We plan to develop a non-invasive, functional 3D-MRE-based method for preoperative regional hepatic functional reserve assessment, and to evaluate its ability to predict surgical risk and postoperative liver failure in patients with HCC undergoing hepatectomy.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 18-80 years
* Pathologically or radiologically confirmed diagnosis of one of the following: hepatocellular carcinoma, intrahepatic cholangiocarcinoma, or liver metastasis (e.g., from colorectal cancer)
* Scheduled to undergo curative hepatectomy
* Child-Pugh class A or B liver function
* Able to tolerate MRI examination
* Provision of signed and dated informed consent
Exclusion Criteria:
* Contraindication to MRI (e.g., non-MRI-compatible implants, severe claustrophobia)
* Child-Pugh class C liver function
* Prior history of liver resection or liver transplantation
* Presence of extrahepatic metastasis
* Emergency surgery (e.g., due to tumor rupture)
* Severe cardiopulmonary or renal dysfunction precluding surgery
* Pregnant or breastfeeding women
* Unwillingness or inability to comply with study procedures or follow-up
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Incidence of Post-Hepatectomy Liver Failure (PHLF)
Timeframe: Within 90 days after surgery
Trial details
NCT IDNCT07704203
SponsorSecond Affiliated Hospital of Xi'an Jiaotong University