Effect of Chromium Weight Reduction on Adult Asthma Control (NCT07703358) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Effect of Chromium Weight Reduction on Adult Asthma Control
60 participantsStarted 2026-08-20
Plain-language summary
This phase IV randomized controlled trial is designed to evaluate the effects of chromium picolinate supplementation in obese adults with stable asthma. A total of 60 participants will be recruited from Ain Shams University Hospitals and randomly assigned to receive either 400 mcg of chromium picolinate daily or a matching placebo for 12 weeks, in addition to standard asthma therapy.
The study aims to explore the interaction between metabolic dysfunction and asthma, as obesity-related asthma is often associated with systemic inflammation, insulin resistance, and dyslipidemia. These factors may contribute to poorer asthma control and impaired pulmonary function, and therefore represent potential targets for adjunctive therapeutic interventions such as chromium supplementation.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age: 18-65 years
* Confirmed asthma diagnosis according to GINA criteria (7)
* Asthma stable for at least 4 weeks (no acute exacerbation)
* BMI of 30 kg/m² (obese category)
* Stable inhaled corticosteroid + LABA regimen in the last 4 weeks
* The patient is compliant on his asthma medication
* Willing and able to provide informed consent
* willing to continue in the study, follow investigator instructions
Exclusion Criteria:
* \- Recent asthma exacerbation (within the last 4 weeks)
* Any change in asthma medications within 4 weeks
* renal or hepatic disease
* Use of lipid-lowering drugs or supplements in the past 3 months
* Use of Vitamin C, prostaglandin inhibitors, such as aspirin, oxalate, and antacids
* Current pregnancy or lactation
* Known allergy to chromium or adverse reaction to supplementation
* Participation in another interventional study in the past month
* History of heavy metal toxicity or chromium sensitivity
* Being on any weight control diet
* Being on a supplement containing chromium
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.