Oral Nicotine Product Messaging to Communicate Risk of Use for Young Adults (NCT07702435) | Clinical Trial Compass
CompletedNot Applicable
Oral Nicotine Product Messaging to Communicate Risk of Use for Young Adults
United States607 participantsStarted 2025-08-01
Plain-language summary
This clinical trial tests the effect of different types of oral nicotine pouch (ONP) messaging to communicate risk of using these products for young adults. Tobacco use remains the leading preventable cause of death due to cancer and other outcomes in the U.S. Tobacco products vary in the health risks they pose to users. Combustible tobacco products such as cigarettes pose higher risks than noncombustible nicotine and tobacco products such as ONPs. Despite the lower harm potential of ONPs for those who use tobacco, there are potential risks to non-users, especially susceptible young adults. Different types of messaging that include information about absolute risk and addiction, risks of ONPs relative to cigarettes and e-cigarettes, ability to use ONPs instead of cigarettes/e-cigarettes (switching), and the potential benefits of doing so and potential benefits of switching to ONPs may be more or less effective in communicating risk for young adults.
Who can participate
Age range
18 Years – 30 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* United States (U.S.) young adults aged 18 - 30 years
* Current cigarette smokers. Current smokers are those who smoked 100 lifetime cigarettes and now are smoking every day or some days
* Current e-cigarette users. Current e-cigarette users are those who have ever tried an e-cigarette or other electronic vaping product even once and are now using every day or some days
* Susceptible nonusers of cigarettes or e-cigarettes. Susceptible nonusers are those who have never tried cigarettes/e-cigarettes and respond with any response other than "definitely not" to any of the following items:
* "Have you ever been curious about using cigarettes/e-cigarettes?"
* "Do you think that you will try a(n) cigarette/e-cigarette soon?"
* "If one of your best friends were to offer you a(n) cigarette/e-cigarette, would you use it?"
* "Do you think you will use cigarettes/e-cigarettes in the next year?"
Exclusion Criteria:
* Participants who do not meet age and tobacco-related criteria, unable to complete study procedures online in English, or do not reside in the U.S. will be excluded
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Perceived Message Effectiveness
Timeframe: This assessment is administered immediately after participants view study messages.
2
Perceived Message Strength
Timeframe: This assessment is administered immediately after participants view study messages.
3
Counterarguing
Timeframe: This assessment is administered immediately after participants view study messages.
4
Negative Feelings
Timeframe: This assessment is administered immediately after participants view study messages.
5
Positive Feelings
Timeframe: This assessment is administered immediately after participants view study messages.
6
Oral Nicotine Pouch Use Curiosity
Timeframe: This assessment is administered immediately after participants view study messages.
7
Oral Nicotine Pouch use intentions
Timeframe: This assessment is administered immediately after participants view study messages.
Trial details
NCT IDNCT07702435
SponsorOhio State University Comprehensive Cancer Center