CompletedNot Applicable

Ionized Calcium Changes for Predicting Postoperative Hypocalcemia After Total Thyroidectomy

Turkey (Türkiye)327 participantsStarted 2025-06-12

Plain-language summary

This prospective observational study aims to evaluate whether changes in ionized calcium levels measured by blood gas analysis during the preoperative, intraoperative, and postoperative periods can predict postoperative hypocalcemia in patients undergoing total thyroidectomy. Ionized calcium values obtained at predefined perioperative time points will be compared with postoperative biochemical and clinical hypocalcemia outcomes.

Who can participate

Age range

18 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients aged 18 to 75 years * Present to the General Surgery Clinic of Başakşehir Çam and Sakura City Hospital * Diagnosis of thyroid disorders according to ICD code E07 * Scheduled to undergo total thyroidectomy due to toxic multinodular goiter, multinodular goiter, or papillary carcinoma * Provide informed consent to participate in the study. Exclusion Criteria: * Patients with preoperative parathyroid disorders associated hypocalcemia or hypercalcemia. * Patients with a history of previous thyroidectomy * Patients with a history of previous parathyroidectomy * Patients with a history of previous neck surgery. * Patients with chronic kidney disease. * Patients with a history of non-thyroid malignancy.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

ionized calcium

Timeframe: Preoperative baseline; postoperative 10 minutes; postoperative 6 hours

parathormone levels

Timeframe: Preoperative baseline; postoperative 10 minutes; postoperative 6 hours; and postoperative 6 months

Trial details

NCT IDNCT07701824

SponsorEmrecan Deniz

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2026-04-25

View on ClinicalTrials.gov More Postoperative Hypocalcemia trials