Fermented Dairy Product and Bifidobacterium Diversity
France115 participantsStarted 2026-08
Plain-language summary
Bifidobacterium strains with potential health benefits can contribute to the gastrointestinal wellbeing. However, the ability of these strains to survive gastro-intestinal tract stress and their impact on gut microbiome remains to be clarified. This is why the current study aims to assess the impact of Bifidobacteria consumption on human gut microbiome compared to control product.
Who can participate
Age range
45 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Male and female subjects aged between 45 and 60 years old.
. BMI between 18.5 kg/m² and 30 kg/m².
. Subjects who are overtly healthy as determined by the investigator.
. Able to speak and read in French.
. Willing and able to collect their faecal samples themselves.
. Having access to adequate space to store the investigational.
. Regular bowel movements.
. Willing to consume the study products twice per day for 28 consecutive days.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
The primary outcome parameter in this study is the change from baseline after 28-days product consumption of the number of distinct Bifidobacterium species.
Timeframe: After 28 days of study product consumption
. Any ongoing metabolic disease, hypertension, inflammatory disease, thyroid disease, allergic conditions requiring chronic systemic medication, psychiatric disorder, gastrointestinal disorder, chronic pain, or neurological disorder diagnosed by a physician.
. Known with allergy or intolerance to any ingredients or allergens.
. Pregnancy or breast-feeding at the screening visit or plan for pregnancy during the study.
. Any antecedents of digestive surgery, or plan for such surgery during the study.
. Any dental surgery within the last 4 weeks before the screening visit, or plan for dental surgery during the study.
. Subject who had any surgery or intervention requiring a general anaesthesia in the preceding 4 weeks before the screening visit, or who plans to have one during the study.
. Unable (or unwilling) to adhere to protocol requirements.
. Subject with a special diet at the screening visit, or plan for such diet during the study.