Photobiomodulation in Coronary Artery Bypass Grafting With No-Touch vs Conventional Saphenous Vei… (NCT07699679) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Photobiomodulation in Coronary Artery Bypass Grafting With No-Touch vs Conventional Saphenous Vein Harvesting.
Brazil292 participantsStarted 2026-08
Plain-language summary
This randomized, double-blind clinical trial aims to evaluate the impact of photobiomodulation therapy on postoperative outcomes in patients undergoing coronary artery bypass grafting (CABG). The study will compare two techniques for saphenous vein graft harvesting: the conventional technique and the no-touch technique. Participants will be randomly allocated into four groups: conventional harvesting with placebo, conventional harvesting with photobiomodulation, no-touch harvesting with placebo, and no-touch harvesting with photobiomodulation. The primary objective is to evaluate the effects of photobiomodulation on wound healing and postoperative complications related to the saphenous vein harvesting site. Secondary outcomes include clinical outcomes and functional capacity after surgery. The results may contribute to improving postoperative recovery and optimizing surgical strategies in patients undergoing myocardial revascularization.
Who can participate
Age range
18 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients diagnosed with coronary artery disease scheduled to undergo elective coronary artery bypass grafting (CABG)
* Use of the saphenous vein as a graft for myocardial revascularization
* Ability to understand the study procedures and provide written informed consent
Exclusion Criteria:
* Emergency coronary artery bypass surgery
* Previous surgery in the lower limb that prevents saphenous vein harvesting
* Active infection at the surgical site or lower limb
* Severe peripheral arterial disease in the lower limbs
* Hemodynamic instability preventing study protocol procedures
* Participation in another interventional clinical trial that may interfere with the outcomes of this study
* Patients unable to perform postoperative functional capacity assessments
* Individuals with highly pigmented skin or sensibility that may alter light absorption and penetration of the photobiomodulation therapy.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Incidence of surgical wound complications at the saphenous vein harvesting site
Timeframe: From postoperative hospitalization to 30 days and 3 months after surgery.
2
Functional capacity assessed by the Six-Minute Walk Test
Timeframe: From preoperatory assessment to postoperative day 5 or at hospital discharge, 30 days and 3 months follow-up.