Pediatric Movement Disorders of Unknown Etiology in Vietnam (VPeMD) (NCT07695610) | Clinical Trial Compass
RecruitingNot Applicable
Pediatric Movement Disorders of Unknown Etiology in Vietnam (VPeMD)
Vietnam50 participantsStarted 2026-04-17
Plain-language summary
This observational patient registry aims to describe the clinical phenotypes and genetic findings of Vietnamese children with movement disorders of unknown etiology. Eligible participants are children with clinically confirmed movement disorders after evaluation by pediatric neurology specialists and after exclusion of clear acquired causes.
The study will collect clinical data, neurological examination findings, available laboratory and imaging results, and video recordings of abnormal movements when consent is provided. Blood samples will be collected for whole-exome sequencing and related genetic analysis. Genetic variants will be classified according to accepted clinical genetics standards and compared with the patients' clinical phenotypes.
The study is expected to improve understanding of the phenotypic and genotypic spectrum of pediatric movement disorders in Vietnam, support genetic counseling, and evaluate how genetic results may influence diagnosis, follow-up, prognosis, and treatment planning.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Children younger than 18 years old.
* Patients with clinically confirmed movement disorders based on direct examination and/or video review by at least two pediatric neurology specialists.
* Patients with movement disorders of unknown etiology after appropriate neurological evaluation and exclusion of clear acquired causes.
* Patients evaluated or treated at University Medical Center Ho Chi Minh City or Children's Hospital 1 during the study period.
* Patients and/or legal guardians who provide written informed consent for study participation and genetic testing.
Exclusion Criteria:
* Patients with isolated or transient primary tic disorders.
* Patients with a confirmed acquired cause of movement disorder.
* Patients or legal guardians who decline participation or withdraw from the study.
* Patients with insufficient clinical information or unavailable biological samples for genetic analysis.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Clinical Phenotypes of Pediatric Movement Disorders
Timeframe: At enrollment
Trial details
NCT IDNCT07695610
SponsorUniversity of Medicine and Pharmacy at Ho Chi Minh City