Cognitive Training for Functioning in PTSD (NCT07693686) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Cognitive Training for Functioning in PTSD
United States176 participantsStarted 2027-07-01
Plain-language summary
The proposed study will test a novel, computerized treatment for posttraumatic stress disorder (PTSD) to determine if it helps Veterans functionally recover as measured by reduced cognitive disability and PTSD symptoms. To do so, investigators will evaluate the effects of a cognitive training program that is designed to improve people's ability to manage information in working memory. Investigators will measure self-reported symptoms and disability alongside day-to-day cognition and functioning. The project support the VA Office of Research and Development's mission to improve Veteran participation in their lives and community by determining if this new approach can improve recovery from trauma and exploring for whom the intervention works.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* diagnosis of PTSD
* presence of subjective cognitive complaints
* fluent in English
* willing to attend assessment and treatment sessions
Exclusion Criteria:
* past year history of psychotic or bipolar I disorders
* past year history of severe alcohol or substance use disorder
* history of severe traumatic brain injury or other known neurological condition that may be associated with cognitive dysfunction
* acute suicidality necessitating immediate clinical intervention (within past 3 months)
* presence of circumstances that require imminent intervention prior to other treatment (e.g., current domestic abuse)
* plans for medication changes within the study timeframe
* current or planned evidence-based psychotherapy for PTSD within the study timeframe
* plans for changes to other psychosocial therapy within the study timeframe
* presence of life-threatening or unstable medical conditions
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in World Health Organization Disability Assessment Schedule (WHODAS 2.0), cognitive domain
Timeframe: baseline, post (week 10), 3-month follow-up, 6-month follow-up