CompletedNot Applicable

Corneal Topography and High Order Aberrations in Regular Contraceptive Pills

Egypt40 participantsStarted 2024-10-01

Plain-language summary

Effect of regular usage of contraceptive pills on corneal topography and corneal high-order aberrations

Who can participate

Age range

18 Years – 40 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Female participants aged 18-40 years. * Prescribed combined oral contraceptive pills as part of routine gynecological care. * Willing to undergo corneal topography/tomography before starting treatment and after 1 year. * No previous history of corneal disease or ocular surgery. * Able to provide informed consent. Exclusion Criteria: * Keratoconus or suspected corneal ectasia. * Corneal opacity, dystrophy, degeneration, or scarring. * Previous ocular surgery or significant ocular trauma. * Current contact lens use or recent contact lens use without adequate discontinuation period. * Active ocular surface disease or severe dry eye. * Glaucoma, uveitis, retinal disease, or other significant ocular pathology. * Diabetes mellitus, autoimmune disease, thyroid disease, pregnancy, or lactation. * Use of other hormonal therapy or systemic medications known to affect corneal parameters.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in K1 (D)

Timeframe: Baseline and 1 year

Change in K2 (D)

Timeframe: one year

Change in Kmax (D)

Timeframe: one year

change in corneal thickness (um)

Timeframe: one year

Trial details

NCT IDNCT07693673

SponsorElshimaa A.Mateen

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-01-30

View on ClinicalTrials.gov More Cornea trials

Who can participate

Age range

18 Years – 40 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.