This single-center randomized controlled trial compared heated humidified high-flow nasal cannula (HHHFNC) with nasal continuous positive airway pressure (nCPAP) as primary noninvasive respiratory support in preterm infants (gestational age 28-34 weeks; birth weight 1000-2000 g) with moderate respiratory distress syndrome. The primary outcome was treatment failure requiring invasive mechanical ventilation within the first 7 days.
Age range
28 Weeks – 34 Weeks
Sex
ALL
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Number of Participants With Treatment Failure Requiring Invasive Mechanical Ventilation
Timeframe: First 7 days of life (assessed at 72 hours, Day 5, and Day 7)