The Effect of Fasting on Peak Fat Oxidation, Mitochondrial Coupling and Extracellular Matrix (NCT07692646) | Clinical Trial Compass
RecruitingNot Applicable
The Effect of Fasting on Peak Fat Oxidation, Mitochondrial Coupling and Extracellular Matrix
Denmark40 participantsStarted 2026-06
Plain-language summary
The interventional study will recruit four groups (n=10 per group): Young men and women with normal weight (BMI 18-25), and young men and women with obesity (BMI \>30). The study will investigate the effect of 84 hours of fasting on peak fat oxidation, mitochondrial coupling and the extracellular matrix.
Who can participate
Age range
18 Years – 40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Healthy normal weight men aged \[18,40\] and BMI \[18,25\]
* Healthy normal weight women \[18,40\] and BMI \[18,25\]
* Healthy obese men \[18,40\] and BMI \[30,40\]
* Healthy obese women \[18,40\] and BMI \[30,40\]
Exclusion Criteria:
* Present or former cardiovascular disease and chronical inflammatory disease
* Consumption of medications and supplements that influence substrate use at rest and/or during exercise
* Pregnancy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
The effect of fasting and obesity on protein glycosylation of the extracellular matrix in adipose tissue
Timeframe: The fasting will last approximately 84 hours.