RecruitingNot Applicable

DL Models Predicting Cycloplegic Refractive Error Based on Non-Cycloplegic Parameters in Myopic Adults

China2,500 participantsStarted 2023-10-03

Plain-language summary

This study presents a machine learning model that predicts cycloplegic refraction in adults with myopia using standard non-cycloplegic eye measurements, aiming to reduce the need for cycloplegic drops while still identifying patients who require them.

Who can participate

Age range

18 Years – 47 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Age 18 to 60 years, of either sex;
. Spherical equivalent between -0.50 diopters and -10.00 diopters, with myopia in one or both eyes, and with cylinder of 4.00 diopters or less;
. Best-corrected visual acuity of 20/25 or better in each eye;
. Clear cornea, no keratoconus, corneal scarring, or other pathologies; clear lens;
. Intraocular pressure of 21 mmHg or less, with no history of glaucoma;
. No history of ocular surgery, especially corneal refractive surgery or cataract surgery;
. Time interval between non-cycloplegic refraction and cycloplegic refraction of 7 days or less, with complete data.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Accuracy of predicted cycloplegic spherical equivalent

Timeframe: Day 0

Trial details

NCT IDNCT07690813

SponsorSecond Affiliated Hospital of Nanchang University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-11-25

Contact for this trial

jian xiong

18170906556 894040417@qq.com

View on ClinicalTrials.gov More Refractive Errors trials

Who can participate

Age range

18 Years – 47 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Age 18 to 60 years, of either sex;
. Spherical equivalent between -0.50 diopters and -10.00 diopters, with myopia in one or both eyes, and with cylinder of 4.00 diopters or less;
. Best-corrected visual acuity of 20/25 or better in each eye;
. Clear cornea, no keratoconus, corneal scarring, or other pathologies; clear lens;
. Intraocular pressure of 21 mmHg or less, with no history of glaucoma;
. No history of ocular surgery, especially corneal refractive surgery or cataract surgery;
. Time interval between non-cycloplegic refraction and cycloplegic refraction of 7 days or less, with complete data.

DL Models Predicting Cycloplegic Refractive Error Based on Non-Cycloplegic Parameters in Myopic Adults

Plain-language summary

Who can participate

Inclusion criteria

Questions worth asking your doctor

Questions for the trial coordinator

What they're measuring

Trial details

Contact for this trial

DL Models Predicting Cycloplegic Refractive Error Based on Non-Cycloplegic Parameters in Myopic Adults

Plain-language summary

Who can participate

Inclusion criteria

Questions worth asking your doctor

Questions for the trial coordinator

What they're measuring

Trial details

Contact for this trial

Exclusion criteria