How the Body Processes Sugar After Eating, in People With Different Body Weights

Inclusion Criteria: * Healthy males and females using contraception during and for 3 months after the study. * Aged from 18-65 years at the time of signing informed consent * 18.5 \< BMI \< 25 kg·m2 or 30\< BMI \<35 kg·m2 * Must be willing and able to communicate and participate in the whole study, including consumption of 14C-glucose and meals offered during study conduct * Must have regular bowel movements (i.e. average stool production of ≥1 and ≤3 stools per day) * Must usually eat 3 meals per day (i.e. breakfast, lunch and dinner) Exclusion Criteria: * Diabetes (Type 1, Type 2, or genetic form of diabetes) * Any diagnosed cardiovascular (heart) disease or high blood pressure (≥140 mmHg systolic and/or ≥90 mmHg diastolic) * HbA1c higher than 53 mmol/mol * History of clinically significant cardiovascular, renal, hepatic, chronic respiratory or gastro-intestinal disease, immunodeficiency, endocrine, neurological, or psychiatric disorders * Any diagnosed respiratory disease, such as COPD or asthma * Any previous motor disorders or disorders in muscle and/or lipid metabolism * Known severe kidney problems * Presence of an ulcer in the stomach or gut and/or strong history of indigestion * Recent or chronic history of diarrhoea * Known anaemia * A personal or family history of thrombosis (clots), epilepsy, seizures, or schizophrenia. * Regular use of dietary supplements (\>3 times per week) * Chronic use of any prescribed or over the counter pharmaceuticals (excluding oral c…