Evaluation of Wear Resistance of CAD/CAM Hybrid Ceramic and Nano-Hybrid Composite Overlays in End… (NCT07689032) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Evaluation of Wear Resistance of CAD/CAM Hybrid Ceramic and Nano-Hybrid Composite Overlays in Endodontically Treated Molars and Their Effect on Natural Antagonist Teeth
24 participantsStarted 2026-07
Plain-language summary
This randomized clinical trial aims to to evaluate and compare the 24-month surface wear of the restoration and the surface wear of the opposing natural tooth structure of CAD/CAM Hybrid Ceramic (SHOFU Hard blocks) versus Resin-based Composite (BRILLIANT Crios) overlays, utilizing a digital subtraction methodology (Intraoral Scanner and Geometrical Subtraction Software) in endodontically treated molar teeth.
Who can participate
Age range
22 Years – 45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age between 22 and 45 years.
* Low to moderate caries risk.
* Normal occlusion.
* Absence of signs or symptoms of temporomandibular joint (TMJ) disorders.
* Satisfactory oral hygiene.
* Medically fit to receive routine restorative dental treatment.
* Permanent molars.
* Asymptomatic endodontically treated teeth.
* Homogeneous root canal fillings extending 1-2 mm from the radiographic apex.
* Compound cavities.
* Favorable occlusion.
* Presence of both an adjacent tooth and a sound opposing tooth in occlusion
Exclusion Criteria:
* \* Presence of bruxism.
* Poor patient cooperation.
* Inability or unwillingness to attend follow-up appointments.
* Anticipated travel during the study period.
* Poor oral hygiene.
* Chronic or advanced periodontitis.
* Known allergies to any of the materials used in the study.
* Patients who are pregnant or breastfeeding.
* Teeth with \<1" mm" of residual wall thickness.
* Deep subgingival cavity margins.
* Severe periodontal problems.
* Radiographic signs of apical pathology.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.