Risk Factors for Postoperative Nausea and Vomiting (PONV) in Adults at the Post-Anaesthesia Care … (NCT07688811) | Clinical Trial Compass
CompletedNot Applicable
Risk Factors for Postoperative Nausea and Vomiting (PONV) in Adults at the Post-Anaesthesia Care Unit of Dr. Cipto Mangunkusumo National General Hospital
Indonesia280 participantsStarted 2026-01-26
Plain-language summary
The goal of this observational study is to determine the incidence of postoperative nausea and vomiting (PONV) and identify its risk factors in adult patients recovering in the post-anaesthesia care unit (PACU) after elective surgery at RSUPN Dr. Cipto Mangunkusumo, Jakarta, Indonesia. The main questions it aims to answer are:
* What is the incidence of PONV among adult patients during their PACU stay?
* Which patient-, anaesthesia-, and surgery-related factors are independently associated with the occurrence of PONV?
Participants who undergo elective surgery under any anaesthetic technique (general anaesthesia, spinal, epidural, or sedation) will be observed for nausea and vomiting from PACU admission until discharge. Researchers will also record the following variables for each participant:
* Patient factors: age, sex, smoking history, and history of motion sickness or prior PONV
* Anaesthesia factors: type of anaesthesia, intraoperative opioid use, and PONV prophylaxis use
* Surgical factors: type of surgery and surgical duration
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adult patients aged 18 years or older
* Scheduled to undergo elective surgery under any type of anaesthesia (general anaesthesia, spinal, epidural, or sedation)
* ASA (American Society of Anesthesiologists) physical status classification I-IV
* Fully conscious with a Glasgow Coma Scale (GCS) score of 15
Exclusion Criteria:
* Presence of nausea or vomiting before anaesthesia induction
* Use of Monitored Anaesthesia Care (MAC) technique
* Preoperative use of opioids or other emetogenic medications
* Patient or legal guardian refuses informed consent
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Incidence of postoperative nausea and/or vomiting (PONV) during PACU stay
Timeframe: Immediate postoperative period (Postoperative Day 0; during PACU stay)