Mental Effort During Low Load Resistance Training in Older Adults (NCT07687316) | Clinical Trial Compass
RecruitingNot Applicable
Mental Effort During Low Load Resistance Training in Older Adults
United States75 participantsStarted 2026-06-06
Plain-language summary
The goal of this clinical trial is to determine the effect of maximal mental effort combined with low-intensity resistance training on strength and neuromuscular function in older adults. The main questions it aims to answer are:
* Does low-intensity resistance training in combination with maximal mental effort increase strength more than low intensity resistance training alone?
* Does low-intensity resistance training in combination with maximal mental effort improve neuromuscular function more than low intensity resistance training alone?
Participants will be randomly assigned to 1 of 3 groups:
* Low intensity resistance training
* Low intensity resistance training with maximal mental effort
* Control Researchers will compare groups to determine differences in changes in strength, neuromuscular function, and body composition.
Who can participate
Age range
65 Years – 85 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Body mass index between 18.5 - 33 kg·m2
* No structured physical activity in past 2 years
* Any unstable condition contradicting exercise
* Independently walk with or without assistive device
* No significant cognitive impairment
Exclusion Criteria:
* Score of 22 or lower on Montreal Cognitive Assessment
* Missing more than 3 training sessions (training groups only)
* Pacemaker
* Unstable angina
* Symptomatic heart failure
* Uncontrolled arrythmias
* Uncontrolled hypertension (greater or equal to 160/90)
* Myocardial infarction in the past 6 months
* Uncontrolled type 2 diabetes
* Type 1 diabetes
* Severe or unstable pulmonary conditions,
* Currently on supplemental oxygen therapy
* Severe hearing loss or visual impairment
* Alzheimer's Disease or significant cognitive impairment
* Stroke in the past 6 months or ongoing stroke-induced motor impairment
* Any neurological (e.g., Parkinson's) condition affecting motor control
* Undergoing chemotherapy
* Surgery in past 6 months
* Musculoskeletal injury in the past 6 months
* Terminal illness
* Stage 3 or greater chronic kidney disease
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in isokinetic strength of the knee extensors at 60 degrees per second