Ovarian Reserve After Laparoscopic Cystectomy for Endometriotic and Non-Endometriotic Cysts (NCT07686783) | Clinical Trial Compass
RecruitingNot Applicable
Ovarian Reserve After Laparoscopic Cystectomy for Endometriotic and Non-Endometriotic Cysts
Egypt60 participantsStarted 2026-06-30
Plain-language summary
We will conduct this study to estimate the effect of laparoscopic cystectomy on ovarian reserve in endometriotic cysts versus non-endometriotic cysts.
Who can participate
Age range
18 Years – 45 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Female patients aged 18-45 years
* Ovarian cyst measuring 6-15 cm in diameter, confirmed by transvaginal ultrasound or MRI
* Cyst is persistent for more than 3 months if asymptomatic, OR any symptomatic cyst regardless of duration of diagnosis
* Serum anti-Müllerian hormone (AMH) level ≥ 2 ng/mL, measured within 1 month preoperatively
* Willingness to participate and provide written informed consent
Exclusion Criteria:
* Clinical or ultrasonic suspicion of ovarian malignancy
* Ovarian cyst associated with pregnancy
* Previous history of ovarian surgery
* History of pelvic irradiation or chemotherapy
* Known endocrine disorders affecting ovarian function (e.g., PCOS, premature ovarian insufficiency, thyroid dysfunction, hyperprolactinemia)
* Current use of hormonal contraceptives or hormonal therapy within 3 months prior to enrollment
* Presence of severe systemic disease that contraindicates surgery or general anesthesia
* Refusal to participate or inability to provide informed consent
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is comparing how ovarian reserve — measured by the AMH hormone — changes after removing endometriotic cysts versus other types of benign ovarian cysts; given my specific diagnosis, which group would I fall into, and does that affect how much this study's findings might apply to my situation?
2AMH is being used as the main measurement of ovarian reserve in this study — can you explain what my current AMH level is and what a meaningful drop after surgery would actually mean for my fertility going forward?
3Since this is listed as a non-interventional or observational phase (Phase NA), does participating in this trial change anything about how my surgery or follow-up care would be managed, or would I simply be tracked and measured alongside my standard treatment?
4I've heard that removing endometriotic cysts can sometimes damage healthy ovarian tissue — is there anything about how this trial monitors that risk that could help us make a more informed decision about whether and when I should have surgery?
5Are there alternative approaches to managing my ovarian cyst — such as medication or watchful waiting — that we should weigh against surgery before deciding whether it makes sense to be part of this study?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Absolute Change in Serum Anti-Müllerian Hormone (AMH) Level
Timeframe: Baseline (preoperative, within 1 month before surgery) and 3 months postoperatively