Individualized Non-pharmacological Intervention for Bowel Preparation
China339 participantsStarted 2026-06-08
Plain-language summary
Colonoscopy is essential for the early detection of colorectal cancer. However, inadequate bowel preparation remains a common challenge, associated with reduced adenoma detection rates, prolonged procedure time, and increased healthcare costs. Current individualized regimens rely largely on higher laxative dosages-an approach with limited clinical utility. Non-pharmacological interventions, including dietary modification, physical activity, and health education, are safe and tend to have better patient adherence. The effectiveness of health education depends largely on message framing. Guided by information-framing theory, we developed an individualized non-pharmacological regimen. This randomized controlled trial aims to evaluate the efficacy of this regimen in improving bowel preparation quality.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* age ≥ 18 years;
* outpatient scheduled for colonoscopy using oral laxatives for bowel preparation;
* able to understand the study and provide written informed consent.
Exclusion Criteria:
* undergoing emergency colonoscopy;
* suspected intestinal obstruction, stricture, or perforation;
* severe cardiac, cerebral, hepatic, or renal disease;
* severe psychiatric disorder;
* impaired consciousness or communication difficulties;
* pregnancy or lactation;
* previous enrollment in this study.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is testing a non-pharmacological approach to bowel preparation for colonoscopy — can you explain what 'individualized non-pharmacological intervention' actually means in practice, and how it differs from the standard laxative prep I'd normally do?
2Since this trial has no assigned phase and is measuring bowel preparation quality as its main outcome, does that mean researchers are still trying to establish whether this approach works as well as conventional prep, and what happens if my bowel preparation turns out to be inadequate on the day of my colonoscopy?
3How would joining this trial affect my colonoscopy experience logistically — for example, would I need extra appointments, follow-up visits, or to follow specific dietary or behavioral instructions leading up to the procedure?
4Given that standard bowel preparation methods already exist, is there a reason my doctor thinks a non-pharmacological approach might be worth exploring in my specific situation, or would sticking with the conventional prep be a safer and more proven path for me right now?
5If I enroll and the individualized intervention doesn't achieve adequate bowel prep quality, would my colonoscopy still go ahead as planned, or could there be delays that might affect the timing of my diagnosis or treatment?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Bowel preparation quality
Timeframe: Assessed by the endoscopist during colonoscopy procedure
Trial details
NCT IDNCT07684716
SponsorGeneral Hospital of Shenyang Military Region