QIPB vs SI-FICB for Postoperative Analgesia After Total Hip Arthroplasty (NCT07683663) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
QIPB vs SI-FICB for Postoperative Analgesia After Total Hip Arthroplasty
Turkey (Türkiye)84 participantsStarted 2026-06-30
Plain-language summary
Total hip arthroplasty (THA) causes moderate-to-severe postoperative pain. The PROSPECT guideline recommends the supra-inguinal fascia iliaca compartment block (SI-FICB) for THA, whereas evidence for newer quadratus-lumborum-family blocks is limited. The quadro-iliac plane block (QIPB) is a recently described fascial plane block, and no study has compared QIPB with SI-FICB head-to-head in any surgical context. In this prospective, double-blind, patients undergoing elective THA who receive one of the two routinely used preoperative blocks (SI-FICB or QIPB, chosen by the attending anesthesiologist as part of routine care) are systematically observed and compared. The primary objective is to assess whether the postoperative analgesic efficacy of QIPB is non-inferior to SI-FICB, using the resting NRS pain score at 6 hours postoperatively as the primary endpoint (non-inferiority margin Δ = 1.3).
Who can participate
Age range
18 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults aged 18-75 years
* Scheduled for elective primary total hip arthroplasty
* ASA physical status I-III
* Able to understand and communicate in Turkish and complete assessment scales
* Completed preoperative anesthesia evaluation and approved for surgery
* Signed written informed consent
Exclusion Criteria:
* Known allergy/contraindication to any local anesthetic, including bupivacaine
* Coagulopathy or anticoagulant/antiplatelet therapy contraindicating block (per ASRA 2022)
* Active infection or skin breakdown at the block site
* Chronic opioid use (≥3 months daily) or history of opioid dependence
* Morbid obesity (BMI \> 40 kg/m²)
* Cognitive impairment or communication difficulty precluding reliable NRS/QoR-15 assessment
* Pregnancy or breastfeeding
* Revision THA or emergency THA for fracture
* Intraoperative complications requiring major protocol deviation (e.g., \>1000 mL blood loss, cardiac arrest)
* Technically failed block (no sensory change at any region on the T1 cold test)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.