An Investigation of the Effect of Vitamin D Level During Frozen Embryo Transfer (FET) in IVF and … (NCT07681115) | Clinical Trial Compass
RecruitingNot Applicable
An Investigation of the Effect of Vitamin D Level During Frozen Embryo Transfer (FET) in IVF and Pregnancy Outcomes
United Arab Emirates126 participantsStarted 2026-06-01
Plain-language summary
Vitamin D is best known for keeping our bones healthy, but growing research suggests it may also play a role in fertility. Many In vitro fertilization (IVF) clinics now routinely check vitamin D levels and prescribe supplements before treatment, but the science is still unclear on whether this actually improves the chances of pregnancy.
Our study, based in the United Arab Emirates (UAE), aims to find out whether a woman's vitamin D level on the day of her frozen embryo transfer (FET) makes a difference to whether she becomes pregnant and delivers a baby. The UAE is an ideal setting for this research, as vitamin D deficiency is particularly common in the region. The findings could shape how fertility clinics screen and treat women seeking fertility treatment in the future.
Who can participate
Age range
18 Years – 40 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion:
* Women undergoing frozen embryo transfer (FET) at Fakih IVF.
* Age between 18 and 40 years.
* Body mass index (BMI) between 18 and 40 kg/m².
* Patients who had serum vitamin D levels assessed within three months prior to FET
* Supplementation with Vitamin D if deficient \< 30 ng/mL (75 nmol/L).
Exclusion:
* Age below 18 years or above 40 years.
* BMI below 18 kg/m² or above 40 kg/m².
* Patients who did not have vitamin D levels measured within three months prior to FET.
* Patients who were found to have low vitamin D levels but did not receive supplementation.
* Patients with recurrent implantation failure (RIF).
* Patients with known uterine factors affecting implantation (e.g., congenital uterine anomalies, intrauterine adhesions, submucosal fibroids).
* Patients with significant medical comorbidities that may affect pregnancy outcomes.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Concentration of serum 25-hydroxyvitamin D levels measured on the day of FET
Timeframe: Vitamin D level tested on the day of FET.
2
Clinical pregnancy test
Timeframe: From enrollment on day of FET to 1 month post FET