Ventilation Mode and Atelectasis After Prone-Position Surgery: A Lung Ultrasound Study (NCT07680881) | Clinical Trial Compass
CompletedNot Applicable
Ventilation Mode and Atelectasis After Prone-Position Surgery: A Lung Ultrasound Study
Turkey (Türkiye)90 participantsStarted 2024-03-01
Plain-language summary
This prospective single-centre observational study compared two intraoperative mechanical ventilation modes, volume-controlled ventilation (VCV) and VCV with AutoFlow/AF, in adults undergoing elective surgery in the prone position. The ventilation mode was selected by the attending anaesthesiologist as part of routine clinical care; the investigators did not assign it. Perioperative atelectasis was assessed using a modified bilateral 12-zone lung ultrasound score obtained before induction of anaesthesia and after extubation, and oxygenation was assessed using the alveolar-arterial oxygen gradient calculated from an intraoperative arterial blood gas sample. The study also examined whether the effect of ventilation mode on atelectasis differed according to obesity.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Consented adults aged 18 to 65 years American Society of Anesthesiologists (ASA) physical status I or II Body mass index below 35 kg/m2 Scheduled for elective surgery in the prone position Oriented and cooperative
Exclusion Criteria:
No consent Pre-existing pulmonary disease Any perioperative lung pathology Inability to complete postoperative lung ultrasound assessment
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Postoperative modified lung ultrasound score
Timeframe: At least 30 minutes after extubation
Trial details
NCT IDNCT07680881
SponsorProf. Dr. Cemil Tascıoglu Education and Research Hospital Organization