The goal of this single-center, nonrandomized, interventional non-profit pilot study is to evaluate the feasibility and clinical utility of a non-invasive near-infrared spectroscopy (NIRS) imaging device for assessing skin-flap tissue oxygen saturation in adult women undergoing mastectomy and immediate breast reconstruction after oncological surgery. The main questions it aims to answer are: * Can NIRS imaging provide reproducible measurements of tissue oxygen saturation (StO₂) in mastectomy skin flaps before surgery, during the intraoperative phase, and during postoperative follow-up? * Can spatial and temporal variations in StO₂ identify areas of potentially reduced flap perfusion or impaired tissue viability? * Can NIRS-derived oxygenation measurements support the assessment of postoperative flap healing and ischemic complications? Participants will: * undergo non-invasive NIRS imaging of the breast skin flap before surgery; * undergo one intraoperative NIRS acquisition during mastectomy and immediate breast reconstruction; * undergo repeated NIRS imaging during postoperative follow-up visits; * receive standard surgical treatment and postoperative care according to routine clinical practice. NIRS imaging is performed for study purposes and does not influence intraoperative surgical decision-making or the choice of reconstructive procedure.
Age range
18 Years – 90 Years
Sex
FEMALE
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Tissue Oxygen Saturation (StO₂) Measured by the Snapshot NIR V3.0 Device
Timeframe: Baseline (preoperative), postoperative day 1, and postoperative day 15 (±5 days).
Correlation Between Snapshot NIR Tissue Oxygen Saturation (StO₂) and Clinical Assessment of Breast Skin Flap Perfusion
Timeframe: Baseline (preoperative), postoperative day 1, and postoperative day 15 (±5 days).
Temporal Change in Tissue Oxygen Saturation (StO₂) of Breast Skin Flaps
Timeframe: Baseline (preoperative), postoperative day 1, and postoperative day 15 (±5 days).