Effects of Protein Type and Mineral Form on Amino Acid Availability (NCT07677098) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Effects of Protein Type and Mineral Form on Amino Acid Availability
Netherlands16 participantsStarted 2026-09-15
Plain-language summary
To compare postprandial plasma amino acid availability, expressed as incremental area under the curve (iAUC), over a 6 hour period following ingestion of 25 g of different protein isolates in healthy, young adults. The primary objective is divided into the following 2 sub-studies, each with 3 comparisons:
* Sub-study 1: whey protein, calcium caseinate, sodium caseinate.
* Sub-study 2: calcium caseinate, magnesium caseinate, potassium caseinate.
Who can participate
Age range
18 Years – 35 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
To be eligible to participate in this study, a participant must meet all of the following criteria:
* Male or female sex
* Aged between 18 - 35 years inclusive
* BMI between 18 - 30 kg/m2
* Healthy, recreationally active (exercise at least once per two weeks and a maximum of four days per week)
* No physical limitations (i.e., able to perform all activities associated with daily living independently)
A potential participant who meets any of the following criteria will be excluded from participation in this study:
* Intolerant to milk protein and/or dairy-based products
* Smoking regularly
* Diagnosed with gastro-intestinal disorders
* Diagnosed with metabolic disorders (e.g. diabetes)
* Diagnosed with musculoskeletal disorders
* Blood donation in the past 2 months
* Females: pregnancy
* Use of any medication known to affect protein metabolism (e.g. corticosteroids, non-steroidal anti-inflammatories or prescribed acne medications)
* Chronic use of gastric acid suppressing drugs (e.g. proton pump inhibitors, H2-antagonists)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is testing how different protein isolates and mineral forms affect amino acid absorption over six hours — since I'm interested in protein metabolism, does my specific situation make me a good candidate to discuss this study with a researcher or dietitian?
2The trial hasn't started recruiting yet — given where I am in my care right now, does it make sense to wait and see if I'd be eligible once it opens, or should I focus on other approaches to address my protein metabolism concerns in the meantime?
3The study involves consuming 25 grams of a specific protein isolate in a single session and measuring blood amino acid levels over six hours — are there any reasons related to my health history, like kidney function or digestive issues, that might make that kind of protocol something to think carefully about?
4Since this is listed as a Phase NA study focused on healthy young adults, what does that mean for how the findings might or might not apply to my own situation, especially if I have any underlying health conditions affecting protein metabolism?
5Are there existing dietary strategies or standard-of-care approaches for supporting healthy protein metabolism that I should consider alongside or instead of waiting for this trial to open?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Six-hour postprandial plasma total amino acid availability following ingestion of 25 grams of different protein isolates in healthy, young adults