CompletedNot Applicable

A Clinical Trial to Evaluate the Effects of a Plant-Based Liquid Supplement on Metabolic Health and Overall Well-Being

United States20 participantsStarted 2025-06-05

Plain-language summary

This single-arm clinical trial will evaluate the effects of a plant-based liquid supplement on metabolic health, digestive health, skin health, and overall well-being. Twenty participants aged 40 to 60 years with elevated alanine transaminase (ALT) or aspartate transaminase (AST) levels will use the supplement daily for 90 days. Participants will complete questionnaires, provide body composition and waist circumference measurements, submit photographs, and undergo blood testing throughout the study. Outcomes include changes in metabolic biomarkers, body composition, digestive symptoms, skin health, and overall well-being.

Who can participate

Age range

40 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 40 to 60 years * Elevated ALT or AST identified during prescreening blood testing * Currently experiencing at least two of the following: Stomach discomfort, Constipation, Diarrhea, Heartburn, Bloating, Gas, Abdominal pain, Skin redness or pimples, Sugar cravings * Willing to comply with study requirements * Willing to discontinue supplements or herbal remedies targeting detoxification, digestive health, liver function, or skin health during the study * Willing to avoid starting new products, medications, or supplements targeting detoxification, digestive health, liver function, or skin health * Willing to maintain normal diet, sleep patterns, and activity levels * Generally healthy without uncontrolled chronic disease * Resides in the United States * Not participating in another research study during the study period * Has access to a study partner to take study photographs Exclusion Criteria: * Severe digestive disorders including acid reflux, IBS, IBD, Crohn's disease, or gastrointestinal tract surgeries * Liver disease * Known allergy or hypersensitivity to study product ingredients Chronic conditions that would interfere with study participation, including oncological or psychiatric disorders * Known severe allergic reactions * Pregnant, breastfeeding, or attempting to conceive * Unwilling to follow study procedures * Stopped hormonal birth control within the past month * History of substance abuse * Use of prescription diabetes medications…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in Body Weight

Timeframe: Baseline, Day 30, Day 60, and Day 90.

Change in Waist Circumference

Timeframe: Baseline, Day 7, Day 30, Day 60, and Day 90.

Change in Body Fat Mass

Timeframe: Baseline, Day 7, Day 30, Day 60, and Day 90.

Change in Lean Body Mass

Timeframe: Baseline, Day 7, Day 30, Day 60, and Day 90.

Change in Visceral Fat Index

Timeframe: Baseline, Day 7, Day 30, Day 60, and Day 90.

Change in Alanine Aminotransferase (ALT)

Timeframe: Baseline, Day 30, Day 60, and Day 90.

Change in Aspartate Aminotransferase (AST)

Timeframe: Baseline, Day 30, Day 60, and Day 90

Trial details

NCT IDNCT07673432

SponsorBiocol Labs

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2026-01-15

View on ClinicalTrials.gov More Metabolic Health trials

Plain-language summary

Who can participate

Age range

40 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change in Body Weight

Timeframe: Baseline, Day 30, Day 60, and Day 90.

Change in Waist Circumference

Timeframe: Baseline, Day 7, Day 30, Day 60, and Day 90.

Change in Body Fat Mass

Timeframe: Baseline, Day 7, Day 30, Day 60, and Day 90.

Change in Lean Body Mass

Timeframe: Baseline, Day 7, Day 30, Day 60, and Day 90.

Change in Visceral Fat Index

Timeframe: Baseline, Day 7, Day 30, Day 60, and Day 90.

Change in Alanine Aminotransferase (ALT)

Timeframe: Baseline, Day 30, Day 60, and Day 90.

Change in Aspartate Aminotransferase (AST)

Timeframe: Baseline, Day 30, Day 60, and Day 90