Tranexamic Acid to Reduce Blood Loss After Varus Derotation Osteotomy

Inclusion Criteria: * Children (aged 4 to 16 years) * Diagnosis of cerebral palsy (CP). CP is an umbrella term under which many specific diagnoses are captured, and the clinical team at the study institution operates a comprehensive referral network to ensure patients with any relevant diagnoses are included. * Gross Motor Function Classification System (GMFCS) levels IV and V, with substantial hip displacement (\>40% migration percentage per Australian Hip Surveillance Guidelines (Wynter M, Gibson N, Kentish M, Love S, Thomason P, Willoughby K, et al. Australian hip surveillance guidelines for children with cerebral palsy 2014. Australian Academy of Cerebral Palsy and Developmental Medicine. 2014.)), who are on the waitlist for bilateral proximal femoral varus derotational osteotomy (VDRO) +/- unilateral or bilateral pelvic osteotomy. Exclusion Criteria: * Haematological disorder (defined as an active genetic or acquired bleeding disorder) * Known hypersensitivity to tranexamic acid (TXA) * Children with promyelocytic leukaemia being treated with oral tretinoin will be excluded from the trial because combination with TXA has resulted in fatal thrombotic complications * Known coagulation defect * Known renal disorder (moderate to severe as per study institution guidelines)