Impact of Periodontitis Grading on Peri-Implant Clinical and Bone Health: A 60-Month Prospective … (NCT07671456) | Clinical Trial Compass
CompletedNot Applicable
Impact of Periodontitis Grading on Peri-Implant Clinical and Bone Health: A 60-Month Prospective Study
70 participantsStarted 2011-01
Plain-language summary
This prospective cohort study evaluated the effect of periodontitis grading on peri-implant clinical and radiographic outcomes over a 60-month follow-up. Fifty-five partially edentulous patients were classified into three groups according to periodontal status: generalized aggressive periodontitis (Grade C), generalized chronic periodontitis (Grade B), and no history of periodontitis. A total of 92 implants (tissue- or bone-level) were placed and restored with single crowns, followed by biannual supportive periodontal therapy.
Peri-implant clinical parameters (probing depth, clinical attachment level, plaque index, and bleeding on probing), marginal bone level changes, peri-implantitis incidence, and implant survival were assessed up to 60 months after prosthetic loading.
The objective was to determine whether periodontal history and grading influence long-term peri-implant outcomes under maintenance therapy.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age ≥ 18 years.
* Previous diagnosis of aggressive periodontitis, chronic periodontitis, or no history of periodontitis.
* Completion of periodontal treatment at least 1 year before study enrollment.
* Enrollment in supportive periodontal therapy.
* Plaque Index \< 20% at study onset.
* Bleeding on Probing \< 20% at study onset.
* Presence of at least one single edentulous space with adjacent teeth.
* Sufficient bone and soft tissue volume for implant placement without the need for reconstructive procedures.
Exclusion Criteria:
* Systemic conditions that contraindicate implant surgery.
* Use of systemic antimicrobial therapy within 6 months before implant placement.
* Untreated or uncontrolled aggressive periodontitis.
* Untreated or uncontrolled chronic periodontitis.
* Pregnancy or breastfeeding.
* Need for bone grafting or soft tissue grafting procedures.
* Current smokers or former smokers.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Marginal bone level changes around dental implants evaluated radiographically.