Pulse Wave Transit Time After Infraclavicular Block (NCT07669688) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Pulse Wave Transit Time After Infraclavicular Block
Turkey (Türkiye)25 participantsStarted 2026-07-20
Plain-language summary
This prospective observational study aims to evaluate the time-dependent changes in Pulse Wave Transit Time (PWTT) following ultrasound-guided infraclavicular brachial plexus block. PWTT is a non-invasive hemodynamic parameter reflecting vascular tone and sympathetic nervous system activity. Patients undergoing upper extremity surgery under infraclavicular block will be monitored using standard perioperative monitoring devices. PWTT measurements will be obtained before and after block placement at predefined time intervals. Secondary outcomes will include perfusion index, skin temperature, heart rate, blood pressure, respiratory rate, and oxygen saturation. The study seeks to determine whether PWTT can serve as an objective and non-invasive marker of sympathetic blockade following infraclavicular block.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients undergoing elective upper extremity hand surgery
* 18 - 65 years
* ASA I
* No coagulopathy, thrombocytopenia, coagulation disorders
* Patients who provide informed consent to participate in the study
Exclusion Criteria:
* History of drug allergy relevant to study procedures or local anesthetics
* Body mass index (BMI) ≥ 30 kg/m²
* Body weight \< 40 kg
* Age \< 18 years or \> 65 years
* History of significant cardiac disease (e.g., arrhythmia, conduction abnormalities)
* Coagulopathy (INR \> 1.5 or platelet count \< 100,000/mm³)
* Pregnancy or lactation
* Infection at the site of peripheral nerve block
* ASA II-IV
* Failed block or motor block duration exceeding 30 minutes
* Patients reporting pain (NRS ≥ 3), due to potential influence on sympathetic activity
* Chronic opioid use
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.