Efficacy of Complex Decongestive Therapy, Exercise and Diet in Women With Lipedema (NCT07667270) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Efficacy of Complex Decongestive Therapy, Exercise and Diet in Women With Lipedema
Turkey (Türkiye)75 participantsStarted 2026-06-15
Plain-language summary
The purpose of this study is to compare the effectiveness of standard physical therapy methods (Complex Decongestive Therapy, Pneumatic Compression, and Exercise) combined with two different nutritional approaches (personalized anti-inflammatory diet vs. standard healthy nutrition education) in women diagnosed with lower extremity lipedema.
Who can participate
Age range
18 Years – 65 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Female, aged 18 to 65 years.
* Clinical and physical examination confirming Stage I, II, or III lipedema.
* Body Mass Index (BMI) \< 45 kg/m\^2.
* Ability to walk without restriction.
Exclusion Criteria:
* Presence of active malignancy.
* Decompensated heart failure.
* Significant lower extremity peripheral artery disease.
* Acute deep vein thrombosis or active thromboembolism.
* Pregnancy.
* Significant sensory loss or severe neuropathy in the lower extremities.
* History of lower extremity liposuction within the last 12 months.
* Active severe infection (e.g., cellulitis).
* Other severe systemic diseases deemed unsafe for the study by researchers.
* Severe non-compliance with the study protocol (e.g., missing \>30% of planned sessions) or participant requesting withdrawal.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.