PENG+LFCN Block vs QIPB for Total Hip Arthroplasty (NCT07667231) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
PENG+LFCN Block vs QIPB for Total Hip Arthroplasty
60 participantsStarted 2026-11-15
Plain-language summary
This randomized clinical trial aims to evaluate and compare the analgesic efficacy and functional outcomes of the quadro-iliac plane block (QIPB) and the pericapsular nerve group (PENG) block combined with lateral femoral cutaneous nerve(LFCN) block in patients undergoing total hip arthroplasty. The primary outcome is the Numeric Rating Scale (NRS) within the first 48 hours after surgery. Secondary outcomes include postoperative total opioid consumption, ıncidence of quadriceps motor block, time to first ambulation, block performance time, falls, length of hospital stay, block- related complications(hematoma,local anesthetic systemic complications, vascular puncture, and infection), patient satisfaction assessed using a Likert scale, and incidence of postoperative nausea and vomiting.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age between 18 and 80 years
* American Society of Anesthesiologists physical status I-III
* Scheduled for elective unilateral primary total hip arthroplasty
* Surgery planned under spinal anesthesia
* Ability to understand and use the Numeric Rating Scale
* Written informed consent provided
Exclusion Criteria:
* Refusal to participate
* Revision total hip arthroplasty
* Bilateral total hip arthroplasty
* Contraindication to spinal anesthesia
* Contraindication to peripheral nerve block
* Known allergy to local anesthetics or study drugs
* Coagulopathy or anticoagulant use incompatible with neuraxial/regional anesthesia
* Infection at the block injection site
* Pre-existing neurological deficit involving the operative lower extremity
* Peripheral neuropathy
* Chronic opioid use
* Cognitive impairment or inability to communicate reliably
* Severe hepatic or renal failure
* Body mass index \>35 kg/m²
* Pregnancy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.