Virtual Reality-Based Mirror Therapy and FES-Cycling in Stroke Rehabilitation (NCT07666308) | Clinical Trial Compass
CompletedNot Applicable
Virtual Reality-Based Mirror Therapy and FES-Cycling in Stroke Rehabilitation
Turkey (Türkiye)60 participantsStarted 2021-05-01
Plain-language summary
This randomized controlled, assessor-blinded study aimed to compare the effects of virtual reality-based mirror therapy (VRBMT) and functional electrical stimulation-assisted cycling (FES-cycling) when combined with conventional rehabilitation on upper extremity recovery in patients with stroke.
Participants with first-ever stroke, unilateral hemiplegia, and upper extremity impairment within six months after stroke onset were randomly assigned to one of three groups: conventional rehabilitation alone, conventional rehabilitation plus VRBMT, or conventional rehabilitation plus FES-cycling.
All participants received a four-week rehabilitation program. Upper extremity motor function, functional independence, use of the affected upper extremity in daily activities, and quality of life were assessed before and after the intervention.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age older than 18 years
* First-ever stroke
* Unilateral hemiplegia
* Time since stroke onset ≤6 months
* Upper extremity Brunnstrom recovery stage between 1 and 4
* Modified Ashworth Scale score \<3 in the affected upper extremity
* Ability to maintain sufficient sitting balance
Exclusion Criteria:
* Visual impairment
* Contraindication to electrical stimulation, including cardiac pacemaker implantation
* Cognitive impairment (Mini-Mental State Examination score \<25)
* Severe aphasia preventing completion of clinical assessments
* Presence of additional neurological disorders, including Parkinson's disease, Alzheimer's disease, multiple sclerosis, neuromuscular junction disorders, motor neuron disease, or peripheral nerve lesions
* Neglect syndrome
* Orthopedic conditions affecting upper extremity function, including amputation or joint contracture
* Severe cardiac disease
* Uncontrolled hypertension
* Epilepsy
* Psychiatric disorders such as schizophrenia or bipolar disorder
* Pregnancy or suspected pregnancy
* Acute deep vein thrombosis or thrombophlebitis
* Local infection at the treatment site
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Upper Extremity Motor Function Assessed by the Fugl-Meyer Assessment